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KMID : 1123920050190010174
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Korean Journal of Oriental Physiology and Pathology
2005 Volume.19 No. 1 p.174 ~ p.178
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Effects of the Bambusae Caulis in Liquamen Extracted by a Different Refining Process on the Hematological and Hepatic Function of the Mouse
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Kim Jeong-Sang
Na Chang-Soo
Jang Kyeong-Seon
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Abstract
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This study was performed to investigate the changes of the hematological and hepatic function in the mouse after the adminstration of Bambusae Caulis in Liquamen extracted by a different refining process during 30 days. The experimental groups divided seven. Control group was administered mice with 0.9％ saline(4mL/kg). The experimental groups were divided 10％ bamboo extract(B1, C1 and D1 experimental groups) and 30％ bamboo extract(B2, C2, D2 experimental groups)administered groups(4mL/kg). Hematological results: RBC(P<0.05) and Hct(P<0.05) were significantly decreased in the D2 group. The activity of transaminase(P<0.05) of D2 group was significantly increased, but the activities of SOD(P<0.05) and catalase(P<0.01) were significantly decreased, in the D group. Histopathological observation: Ballooned hepatocytes were occurred periportal vein in the D1 and D2 groups, and necrosis of hepatic nuclei in the D2 group were observed. The results indicated that hematological and histopathological toxicity were occurred in the administered group of bamboo extract D refined by 2 times distilling at .
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KEYWORD
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Histopathological changes, SOD, Catalase, Bambusae Caulis in Liquamen
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